Surprisingly Simple Mechanical Behavior of a Complex Embryonic Tissue

Surprisingly Simple Mechanical Behavior of a Complex Embryonic Tissue

BACKGROUND Previous studies suggest that mechanical feedback could coordinate morphogenetic events in embryos. Furthermore, embryonic tissues have complex structure and composition and undergo large deformations during morphogenesis. Hence we expect highly non-linear and loading-rate dependent tissue mechanical properties in embryos. METHODOLOGY/PRINCIPAL FINDINGS We used micro-aspiration to ...

A surprisingly simple de Bruijn sequence construction

Pick any length n binary string b1b2 · · · bn and remove the first bit b1. If b2b3 · · · bn1 is a necklace then append the complement of b1 to the end of the remaining string; otherwise append b1. By repeating this process, eventually all 2 binary strings will be visited cyclically. This shift rule leads to a new de Bruijn sequence construction that can be generated in O(1)-amortized time per b...

Complex Behavior of Simple Systems

Since the seminal work of Lorenz [1963] and Rössler [1976], it has been known that complex behavior (chaos) can occur in systems of autonomous ordinary differential equations (ODEs) with as few as three variables and one or two quadratic nonlinearities. Many other simple chaotic systems have been discovered and studied over the years, but it is not known whether the algebraically simplest chaot...

A Simple Mechanism for Complex Social Behavior

The evolution of cooperation is a paradox because natural selection should favor exploitative individuals that avoid paying their fair share of any costs. Such conflict between the self-interests of cooperating individuals often results in the evolution of complex, opponent-specific, social strategies and counterstrategies. However, the genetic and biological mechanisms underlying complex socia...

Modeling the Mechanical Behavior of Adipose Tissue